Sinkala E, Sollier-Christen E, Renier C, Rosàs-Canyelles E, Che J, Heirich K, Duncombe TA, Vlassakis J, Yamauchi KA, Huang H, Jeffrey SS, Herr AE. Profiling protein expression in circulating tumour cells using microfluidic western blotting.
Time:
Nov 06,2023
Sinkala E, Sollier-Christen E, Renier C, Rosàs-Canyelles E, Che J, Heirich K, Duncombe TA, Vlassakis J, Yamauchi KA, Huang H, Jeffrey SS, Herr AE. Profiling protein expression in circulating tumour cells using microfluidic western blotting. Nat Commun. 2017 Mar 23;8:14622. doi: 10.1038/ncomms14622. PMID: 28332571; PMCID: PMC5376644.
Single cell WB 具有的痕量檢測特點(diǎn)，可在 一次普通的抽血中（2-4 ml 血液），檢測到單個(gè)循環(huán)腫瘤細(xì)胞（CTC）多種蛋白標(biāo)志物，為液體活檢提供更精準(zhǔn)的診斷標(biāo)志物。能夠在單個(gè)循環(huán)腫瘤細(xì)胞上檢測多種蛋白質(zhì) marker，為液體活檢提供更精準(zhǔn)的診斷 marker。
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